Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410354 | 0.83 | TGM2 (0.46) | TGM2GSTO1MAOAMAOBF13A1 | |
| SCHEMBL25247069 | 0.83 | TGM2 (0.46) | TGM2GSTO1MAOAMAOBF13A1 | |
| SCHEMBL25294152 | 0.77 | TGM2 (0.46) | TGM2GSTO1MAOAMAOBF13A1 | |
| SCHEMBL29204707 | 0.76 | TGM2 (0.42) | TGM2MAOAMAOBF13A1LMNA | |
| SCHEMBL2243240 | 0.75 | TGM2 (0.45) | TGM2MAOAMAOBF13A1LMNA | |
| SCHEMBL26243787 | 0.74 | WDR5 (0.44) | — | |
| SCHEMBL1369735 | 0.74 | TGM2 (0.56) | TGM2GSTO1F13A1LMNATGM1 | |
| SCHEMBL16634556 | 0.73 | TGM2 (0.42) | TGM2MAOAMAOBF13A1LMNA | |
| SCHEMBL25393645 | 0.71 | TGM2 (0.40) | TGM2GSTO1FGFR4BTKITK | |
| SCHEMBL30599491 | 0.71 | TGM2 (0.40) | TGM2GSTO1FGFR4BTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |