Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | RB1 | P06400 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699273 | 0.73 | LMNA (0.65) | KDM4ELMNAALDH1A1MAPTTNKS | |
| SCHEMBL29367625 | 0.73 | LMNA (0.65) | KDM4ELMNAALDH1A1MAPTTNKS | |
| SCHEMBL21463566 | 0.72 | AURKA (0.44) | KDM4ELMNAMAPTTNKS | |
| SCHEMBL30615531 | 0.72 | AURKA (0.44) | KDM4ELMNAMAPTTNKS | |
| SCHEMBL23119669 | 0.70 | LMNA (0.67) | KDM4ESMN1; SMN2LMNAMAPTTNKS | |
| SCHEMBL4098385 | 0.70 | AURKA (0.56) | KDM4ESMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9994946 | 0.70 | HTT (0.56) | KDM4ELMNAMAPTTNKSMEN1 | |
| SCHEMBL8156714 | 0.70 | GABRP (0.52) | KDM4ELMNAMAPTTNKSMEN1 | |
| SCHEMBL8355420 | 0.69 | KDM4E (0.67) | PARGKDM4ESMN1; SMN2RECQLLMNA | |
| SCHEMBL2225334 | 0.69 | KDM4E (0.67) | PARGKDM4ESMN1; SMN2RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |