Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634625 | 1.00 | HCAR3 (0.52) | HCAR3KMT2ACREBBPMEN1MAPT | |
| SCHEMBL16634741 | 0.89 | KMT2A (0.55) | HCAR3KMT2ACREBBPMEN1MAPT | |
| SCHEMBL16634739 | 0.89 | KMT2A (0.55) | HCAR3KMT2ACREBBPMEN1MAPT | |
| SCHEMBL16634747 | 0.85 | CREBBP (0.46) | HCAR3KMT2ACREBBPMEN1MAPT | |
| SCHEMBL20985435 | 0.80 | ALDH1A1 (0.38) | HCAR3KMT2ACREBBPMEN1MAPT | |
| SCHEMBL20985427 | 0.79 | HCAR3 (0.49) | HCAR3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20985428 | 0.79 | HCAR3 (0.49) | HCAR3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16634569 | 0.77 | KMT2A (0.57) | HCAR3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL16634572 | 0.77 | KMT2A (0.57) | HCAR3KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3811958 | 0.74 | KMT2A (0.64) | KMT2ACREBBPMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |