Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2477029 | 0.98 | ALDH1A1 (0.34) | ALDH1A1TSHRHSD17B10HPGDIDO1 | |
| SCHEMBL6051981 | 0.79 | ESR1 (0.34) | — | |
| SCHEMBL1156230 | 0.79 | HTT (0.46) | ALDH1A1TSHRHSD17B10HPGDHTT | |
| SCHEMBL9172800 | 0.78 | ESR1 (0.33) | — | |
| SCHEMBL6267453 | 0.76 | HPGD (0.37) | ALDH1A1TSHRHSD17B10HPGDCYP3A4 | |
| SCHEMBL14468054 | 0.76 | HTT (0.39) | ALDH1A1HTTGRIN1GRIN2DGRIN3B | |
| SCHEMBL22965656 | 0.76 | AMY1A (0.36) | HTT | |
| SCHEMBL8624057 | 0.76 | SELL (0.39) | ALDH1A1IDO1DAORECQL | |
| SCHEMBL3443090 | 0.73 | CA12 (0.47) | ALDH1A1TSHRHSD17B10HPGDCYP3A4 | |
| SCHEMBL4609294 | 0.72 | RHEB (0.33) | HTTGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478669-A1 | PROCESS OF PREPARING A PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR, AND PRECURSORS THEREOF | Kezar Life Sciences (US) | 2019-05-08 | — | — | EP | claimed |
| WO-2018005781-A1 | PROCESS OF PREPARING A PEPTIDE EPOXYKETONE IMMUNOPROTEASOME INHIBITOR, AND PRECURSORS THEREOF | KEZAR LIFE SCIENCES (US) | 2018-01-04 | — | — | WO | claimed |
| EP-2655527-A1 | PROCESS FOR CURING SURFACE-COATING COMPOSITIONS | ALLNEX AUSTRIA GmbH (AT) | 2013-10-30 | — | — | EP | claimed |
| WO-2012085016-A1 | PROCESS FOR CURING SURFACE-COATING COMPOSITIONS | CYTEC AUSTRIA GMBH (AT) | 2012-06-28 | — | — | WO | claimed |
| EP-2181118-A1 | PROCESS FOR THE PRODUCTION OF PRAMLINTIDE | LONZA AG (CH) | 2010-05-05 | — | — | EP | claimed |
| WO-2009003666-A1 | PROCESS FOR THE PRODUCTION OF PRAMLINTIDE | LONZA AG (CH) | 2009-01-08 | — | — | WO | claimed |
| EP-1917272-A1 | NOVEL COUPLING AGENT AND USES THEREOF | Luxembourg Industries Ltd. (IL) | 2008-05-07 | — | — | EP | claimed |
| WO-2007020620-A1 | NOVEL COUPLING AGENT AND USES THEREOF | LUXEMBOURG INDUSTRIES LTD. (IL) | 2007-02-22 | — | — | WO | claimed |
| CN-1798757-A | Process for the preparation of steroidal carbothioic acid derivatives and intermediates | ALPHARMA APS (DK) | 2006-07-05 | — | — | CN | claimed |
| EP-1611149-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | Alpharma APS (DK) | 2006-01-04 | — | — | EP | claimed |
| WO-2004087731-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | ALPHARMA APS (DK) | 2004-10-14 | — | — | WO | claimed |
| EP-4255469-A1 | ACYLATED SINGLE-CHAIN INSULIN ANALOGUES | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023154907-A1 | USES AND FORMULATIONS OF CAMPTOTHECIN (CPT)-CONTAINING NANOPARTICLES | Dantari, Inc. (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-4161481-A1 | ANTIBACTERIAL SYNTHETIC-BIOINFORMATIC NATURAL PRODUCTS AND USES THEREOF | The Rockefeller University (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4132960-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE SIDE CHAIN | Fresenius Kabi Oncology Limited (IN) | 2023-02-15 | — | — | EP | disclosed |
| EP-0125756-A2 | Fused imidazole compounds, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| EP-0124889-A2 | Process for the preparation of cephalosporins | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-14 | — | — | EP | disclosed |
| EP-0098615-A1 | 1-Oxadethiacephalosporin compound and antibacterial agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1984-01-18 | — | — | EP | disclosed |
| EP-0035689-A1 | 4-Substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-16 | — | — | EP | disclosed |
| EP-0030630-A2 | 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-24 | — | — | EP | disclosed |