Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16647898 | 1.00 | MAPT (0.32) | MAPT | |
| SCHEMBL16635198 | 0.71 | — | — | |
| SCHEMBL6922736 | 0.67 | NOS1 (0.42) | MAPT | |
| SCHEMBL8958622 | 0.67 | NOS1 (0.42) | MAPT | |
| SCHEMBL17964259 | 0.61 | FAAH (0.37) | — | |
| SCHEMBL1200286 | 0.60 | PRSS1 (0.34) | — | |
| SCHEMBL3068 | 0.60 | FAAH (0.33) | — | |
| SCHEMBL19285136 | 0.60 | FAAH (0.33) | — | |
| SCHEMBL19285328 | 0.60 | FAAH (0.33) | — | |
| SCHEMBL22273276 | 0.60 | FAAH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055302-A1 | SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052264-A1 | SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-16 | — | — | WO | disclosed |