Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTRC | Q99895 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576371 | 0.84 | — | — | |
| SCHEMBL11996749 | 0.74 | — | — | |
| SCHEMBL16635198 | 0.72 | — | — | |
| SCHEMBL576860 | 0.72 | — | — | |
| SCHEMBL17135318 | 0.71 | ALDH1A1 (0.42) | PRSS1CTRCF2FAAH | |
| SCHEMBL30570615 | 0.71 | KMT2A (0.33) | — | |
| SCHEMBL24713676 | 0.70 | FAAH (0.35) | PRSS1CTRCF2FAAH | |
| SCHEMBL14640336 | 0.70 | FAAH (0.35) | PRSS1CTRCF2FAAH | |
| SCHEMBL19285136 | 0.69 | FAAH (0.33) | PRSS1CTRCF2FAAH | |
| SCHEMBL3068 | 0.69 | FAAH (0.33) | PRSS1CTRCF2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177522-B1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU PHARMA CO LTD (CN) | 2013-09-04 | — | — | EP | disclosed |
| US-8318716-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-11-27 | — | — | US | disclosed |
| US-8293895-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-10-23 | — | — | US | disclosed |
| US-20110160177-A1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU (HAINAN) BIOPHARMACEUTICAL CO., LTD. (CN) | 2011-06-30 | — | — | US | disclosed |
| US-20110046107-A1 | SULFONYL-SUBSTITUTED CARBAPENEM COMPOUNDS | KBP BIOSCIENCES CO., LTD. (CN) | 2011-02-24 | — | — | US | disclosed |
| CN-101952290-A | Sulfonyl-substituted carbapenem compounds | KBP BIOMEDICAL CO LTD | 2011-01-19 | — | — | CN | disclosed |
| US-20100197653-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP BIOSCIENCES CO., LTD. (CN) | 2010-08-05 | — | — | US | disclosed |
| CN-101720326-A | Novel carbapenem derivatives | KBP BIOSCIENCES CO LTD | 2010-06-02 | — | — | CN | disclosed |
| EP-2186814-A1 | SULFONYL-SUBSTITUTED CARBAPENEM COMPOUNDS | KBP Biosciences Co., Ltd. (CN) | 2010-05-19 | — | — | EP | disclosed |
| CN-101711251-A | 1 beta-methyl carbapenem antibiotic and its pharmaceutical composition and use | KBP BIOMEDICAL CO LTD | 2010-05-19 | — | — | CN | disclosed |
| EP-2177522-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP Biosciences Co., Ltd. (CN) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046107-A1 | SULFONYL-SUBSTITUTED CARBAPENEM COMPOUNDS | SI, TREH, STS | PRSS1 45/4885CTRC 184/4885F2 3233/4885 |
| US-20110160177-A1 | NOVEL CARBAPENEM DERIVATIVES | MGAM, RPIA, MGAM2 | PRSS1 56/4885CTRC 1076/4885F2 2377/4885 |
| US-20100197653-A1 | NOVEL CARBAPENEM DERIVATIVES | SI, MGAM, IDE | PRSS1 42/4885CTRC 542/4885F2 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.