Sugi Predict

Sugi Predict / Compounds / SCHEMBL1663548

SCHEMBL1663548

SCHEMBL1663548

O=Cc1ccc(N2CCC(O)CC2)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.45
▸ ABCG2 Q9UNQ0 1/20 0.45
▸ CHRM2 P08172 1/20 0.40
▸ CHRM4 P08173 1/20 0.40
▸ CHRM5 P08912 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ CHRM3 P20309 1/20 0.40
▸ ALDH1A1 P00352 9/20 0.37
▸ MAPT P10636 9/20 0.37
▸ KMT2A Q03164 6/20 0.37
▸ KDM4E B2RXH2 5/20 0.37
▸ MEN1 O00255 5/20 0.37
▸ LMNA P02545 4/20 0.37
▸ GAA P10253 3/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ATIC P31939 3/20 0.36
▸ ALOX12 P18054 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ CASP7 P55210 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32676039 0.90 ABCB1 (0.39) ABCB1ABCG2CHRM2CHRM4CHRM5
SCHEMBL8702014 0.80 ALDH1A1 (0.49) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL32676230 0.80 ALDH1A1 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL32676141 0.78 ALDH1A1 (0.51) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL1260268 0.78 ALDH1A1 (0.51) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL31178703 0.77 CA2 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL14220701 0.75 ABCB1 (0.41) ABCB1ABCG2CHRM2CHRM4CHRM5
SCHEMBL1432800 0.75 ALDH1A1 (0.55) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL1432603 0.75 AOC3 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL1555679 0.75 TDP1 (0.51) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116376115-A Preparation method of zirconium phosphate flame retardant loaded with organic phosphorus and flame-retardant semi-aromatic polyamide composition 合聚高分子材料科技(广东)有限公司 2023-07-04 — — CN claimed
CN-110563765-B Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant 青岛玉城科技有限公司 2022-01-14 — — CN claimed
CN-110563765-A Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant 青岛玉城科技有限公司 2019-12-13 — — CN claimed
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2026-02-19 — — US disclosed
WO-2024226717-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2024-10-31 — — WO disclosed
CN-116376115-A Preparation method of zirconium phosphate flame retardant loaded with organic phosphorus and flame-retardant semi-aromatic polyamide composition 合聚高分子材料科技(广东)有限公司 2023-07-04 — — CN disclosed
CN-110563765-B Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant 青岛玉城科技有限公司 2022-01-14 — — CN disclosed
CN-110563765-A Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant 青岛玉城科技有限公司 2019-12-13 — — CN disclosed
US-9622991-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2017-04-18 — — US disclosed
EP-2332905-B1 BCRP/ABCG2 Inhibitor YAKULT HONSHA KK (JP) 2017-03-01 — — EP disclosed
US-9144557-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2015-09-29 — — US disclosed
EP-2332905-A1 BCRP/ABCG3 Inhibitor Kabushiki Kaisha Yakult Honsha (JP) 2011-06-15 — — EP disclosed
WO-2011046954-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2011-04-21 — — WO disclosed
CN-101883767-A Abcg2 inhibitor YAKULT HONSHA KK 2010-11-10 — — CN disclosed
US-20100249089-A1 ABCG2 INHIBITOR KABUSHIKI KAISHA YAKULT HONSHA (JP) 2010-09-30 — — US disclosed
US-20100249089-A1 ABCG2 INHIBITOR KABUSHIKI KAISHA YAKULT HONSHA (JP) 2010-09-30 — — US disclosed
US-20100249089-A1 ABCG2 INHIBITOR KABUSHIKI KAISHA YAKULT HONSHA (JP) 2010-09-30 — — US disclosed
EP-2218719-A1 ABCG2 INHIBITOR Kabushiki Kaisha Yakult Honsha (JP) 2010-08-18 — — EP disclosed
US-20090253656-A1 BCRP/ABCG2 INHIBITOR KABUSHIKI KAISHA YAKULT HONSHA (JP) 2009-10-08 — — US disclosed
EP-1864972-A1 BCRP/ABCG2 INHIBITOR Kabushiki Kaisha Yakult Honsha (JP) 2007-12-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249089-A1 ABCG2 INHIBITOR ABCC1, ABCB1, ABCC5 ABCB1 2/4885ABCG2 7/4885CHRM2 4885/4885
US-20090253656-A1 BCRP/ABCG2 INHIBITOR ABCC1, ABCB1, BRCA1 ABCB1 2/4885ABCG2 7/4885CHRM2 4214/4885
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE STRA6, TCOF1, CLIC1 ABCB1 2261/4885ABCG2 1466/4885CHRM2 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.