Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16947953 | 0.90 | FOLH1 (0.48) | FOLH1ALB | |
| SCHEMBL16947836 | 0.90 | FOLH1 (0.48) | FOLH1ALB | |
| SCHEMBL23974073 | 0.86 | LTA4H (0.46) | ALDH1A1CYP1A2LTA4HCASP2BLM | |
| SCHEMBL15626856 | 0.84 | ALB (0.54) | ALDH1A1FOLH1ALBMMP2MMP9 | |
| SCHEMBL21242815 | 0.84 | FOLH1 (0.41) | ALDH1A1CYP1A2LTA4HCASP2FOLH1 | |
| SCHEMBL12413859 | 0.83 | CYP1A2 (0.52) | ALDH1A1CYP1A2LTA4HCASP2BLM | |
| SCHEMBL19069567 | 0.83 | CASP2 (0.59) | ALDH1A1CYP1A2LTA4HCASP2BLM | |
| SCHEMBL21242734 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP1A2LTA4HCASP2FOLH1 | |
| SCHEMBL20055001 | 0.81 | CASP2 (0.52) | ALDH1A1CYP1A2CASP2ACE2NAAA | |
| SCHEMBL16948010 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP1A2LTA4HFOLH1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274801-A1 | ACYLATED GLUCAGON ANALOGUES | NOVO NORDISK AS (DK) | 2015-10-01 | — | — | US | disclosed |
| US-20150210745-A1 | Double-Acylated GLP-1 Derivatives with a Linker | NOVO NORDISK AS (DK) | 2015-07-30 | — | — | US | disclosed |
| US-9006178-B2 | Double-acylated GLP-1 derivatives with a linker | NOVO NORDISK A/S (DK) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210745-A1 | Double-Acylated GLP-1 Derivatives with a Linker | GLP1R, VIP, IAPP | ALDH1A1 3185/4885CYP1A2 3742/4885LTA4H 3203/4885 |
| US-20150274801-A1 | ACYLATED GLUCAGON ANALOGUES | GLP1R, GCG, IAPP | ALDH1A1 3925/4885CYP1A2 3949/4885LTA4H 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.