Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638262 | 0.86 | ALDH1A1 (0.44) | LTA4HALDH1A1CYP1A2ITGB3ITGA2B | |
| SCHEMBL12891254 | 0.83 | EPHX2 (0.51) | ALDH1A1ITGB3ITGA2BCASP2LMNA | |
| SCHEMBL19438356 | 0.83 | CASP2 (0.61) | CASP2NAAA | |
| SCHEMBL20873621 | 0.83 | CASP2 (0.61) | CASP2NAAA | |
| SCHEMBL19069567 | 0.82 | CASP2 (0.59) | LTA4HALDH1A1CYP1A2CASP2BLM | |
| SCHEMBL12413859 | 0.82 | CYP1A2 (0.52) | LTA4HALDH1A1CYP1A2GABRR1CASP2 | |
| SCHEMBL20055001 | 0.80 | CASP2 (0.52) | ALDH1A1CYP1A2CASP2ACE2NAAA | |
| SCHEMBL25878486 | 0.80 | CASP2 (0.57) | CASP2NAAAMEN1KMT2ANOD1 | |
| SCHEMBL13120985 | 0.80 | CASP2 (0.57) | CASP2NAAAMEN1KMT2ANOD1 | |
| SCHEMBL20038715 | 0.80 | LTA4H (0.50) | LTA4HCYP1A2ITGB3ITGA2BGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903825-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | Coherent Biopharma (Suzhou), Limited (CN) | 2021-11-03 | — | — | EP | disclosed |