Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | HTR1A | P08908 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | HTR2C | P28335 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | KRAS | P01116 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.60 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.60 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.60 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.60 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.60 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.60 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301544 | 1.00 | GAA (1.00) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL28914840 | 0.89 | GAA (0.79) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL30122806 | 0.89 | GAA (0.79) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL15884131 | 0.88 | GAA (0.78) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL13952231 | 0.87 | GAA (0.77) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL2743909 | 0.87 | ALDH1A1 (0.77) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL2743907 | 0.87 | ALDH1A1 (0.77) | GAAHTTALDH1A1KDM4EHTR1A | |
| SCHEMBL6106506 | 0.85 | ALDH1A1 (0.74) | GAAHTTALDH1A1KDM4EHTR1A | |
| Sinapic Acid Methyl Ether SCHEMBL207442 | 0.85 | KDM4E (1.00) | GAAHTTALDH1A1KDM4EHTR1A | |
| Sinapic Acid Methyl Ether SCHEMBL207441 | 0.85 | KDM4E (1.00) | GAAHTTALDH1A1KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230301984-A1 | CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230301984-A1 | CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-28 | — | — | US | disclosed |
| CN-113304129-B | Application of mono-ketene monocarbonyl curcumin analogue in preparing antioxidant drugs | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2022-11-08 | — | — | CN | disclosed |
| WO-2022158624-A1 | NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME | 연세대학교 산학협력단 | 2022-07-28 | — | — | WO | disclosed |
| CN-112266352-B | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-112266352-A | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2021-01-26 | — | — | CN | disclosed |
| US-10238631-B2 | Sesquiterpene derivatives and their use in inflammation or cancer treatment | ACADEMIA SINICA (TW) | 2019-03-26 | — | — | US | disclosed |
| US-9908893-B2 | Thieno [2,3-b] pyridines as multidrug resistance modulators | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2018-03-06 | — | — | US | disclosed |
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |
| US-9796671-B2 | Aurora kinase inhibitors | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-24 | — | — | US | disclosed |
| US-8524744-B2 | preventing and/or treating the diseases related to the plaque-activating factors, especially in anti-inflammation and immunization, more especially in the treatment of the acute or chronic inflammation, such as, osteoarthritis, oarthritis deformans, etc. | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-09-03 | — | — | US | disclosed |
| US-20090043109-A1 | ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE | SENSOPATH TECHNOLOGIES, INC. | 2009-02-12 | — | — | US | disclosed |
| US-20080221106-A1 | Arylamine Ketones, Their Preparation Methods, The Pharmaceutical Composition Containing Them And Their Use | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2008-09-11 | — | — | US | disclosed |
| CN-101146772-A | Arylamine ketone compound, synthesis method thereof, pharmaceutical composition containing arylamine ketone compound and application of arylamine ketone compound | INST MATERIA MEDICA CAMS (CN) | 2008-03-19 | — | — | CN | disclosed |
| EP-1783115-A1 | ARYLAMINE KETONES, THEIR PREPARATION METHODS, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2007-05-09 | — | — | EP | disclosed |
| EP-0316790-B1 | RHODANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-4927958-A | ANTIULCER | HOFFMANN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4897406-A | CHEMICAL MEDIATOR INHIBITORS INCLUDING LEUKOTRIENES; ANTIALLERGENS; BRONCHODILATOR AND ANTIICHEMIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0316790-A1 | Rhodanine derivatives, a process for their preparation, pharmaceutical compositions and their use | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0282897-A2 | Ethynyl- and ethenylstyryl ketones | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221106-A1 | Arylamine Ketones, Their Preparation Methods, The Pharmaceutical Composition Containing Them And Their Use | AHR, KYNU, AADAC | GAA 1323/4885HTT 158/4885ALDH1A1 854/4885 |
| US-20090043109-A1 | ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE | ALDH1B1, ALDH2, ALDH3A1 | GAA 3330/4885HTT 2707/4885ALDH1A1 7/4885 |
| US-10238631-B2 | Sesquiterpene derivatives and their use in inflammation or cancer treatment | GSTK1, GSTA1, GTPBP10 | GAA 1071/4885HTT 1703/4885ALDH1A1 1957/4885 |
| US-20230301984-A1 | CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION | ALDH1A2, PDE6D, PDE6C | GAA 359/4885HTT 477/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.