Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286888 | 0.83 | MRGPRX4 (0.34) | DPP4TRPV4KIF11MRGPRX4 | |
| SCHEMBL13185576 | 0.81 | TRPV4 (0.35) | DPP4TRPV4MRGPRX4KCNH2ADRB1 | |
| SCHEMBL20256735 | 0.81 | DPP4 (0.38) | DPP4TRPV4KIF11DPP8MRGPRX4 | |
| SCHEMBL19634004 | 0.81 | MRGPRX4 (0.36) | DPP4KIF11MRGPRX4CYP2D6ADRB1 | |
| SCHEMBL19568082 | 0.81 | DPP4 (0.34) | DPP4TRPV4KIF11DPP8MRGPRX4 | |
| SCHEMBL13160946 | 0.79 | GABRA1 (0.41) | DPP4DPP8CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL16400368 | 0.78 | TRPV4 (0.32) | TRPV4KIF11 | |
| SCHEMBL19566851 | 0.78 | HRH4 (0.33) | DPP4KCNH2ADRB1ADRA2AADRB3 | |
| SCHEMBL20782181 | 0.76 | ADRB1 (0.33) | DPP4TRPV4ADRB1ADRA2AADRB3 | |
| SCHEMBL29430341 | 0.75 | DPP4 (0.46) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161273-B1 | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment | LEUVEN K U RES & DEV (BE) | 2015-04-15 | — | — | EP | disclosed |