Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 9/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302880 | 0.80 | NOX4 (0.50) | NOX4PDE10AHCRTR1HCRTR2 | |
| SCHEMBL19956784 | 0.74 | NOX4 (0.57) | NOX4PDE10A | |
| SCHEMBL1302281 | 0.73 | NOX4 (0.60) | NOX4PDE10A | |
| SCHEMBL2217002 | 0.66 | NOX4 (0.56) | NOX4 | |
| SCHEMBL1302839 | 0.62 | NOX4 (0.78) | NOX4 | |
| SCHEMBL1302350 | 0.61 | NOX4 (1.00) | NOX4 | |
| SCHEMBL1302902 | 0.61 | NOX4 (0.82) | NOX4 | |
| SCHEMBL19634008 | 0.59 | PDE10A (0.52) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL2214964 | 0.59 | NOX4 (1.00) | NOX4 | |
| SCHEMBL19956827 | 0.59 | PGR (0.48) | NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860179-A1 | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors | GenKyoTex SA (CH) | 2015-04-15 | — | — | EP | disclosed |