Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801086 | 0.82 | ALDH1A1 (0.63) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL3764257 | 0.80 | RAB9A (0.55) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL16672087 | 0.80 | TXNRD1 (0.44) | TXNRD1L3MBTL1KMT2ARAB9AMEN1 | |
| SCHEMBL12469879 | 0.79 | TXNRD1 (1.00) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL11927841 | 0.79 | RAB9A (0.54) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL12831174 | 0.77 | RAB9A (0.52) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL11228519 | 0.77 | L3MBTL1 (0.52) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL16638891 | 0.76 | TXNRD1 (0.67) | TXNRD1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11237984 | 0.76 | RAB9A (0.51) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 | |
| SCHEMBL17070835 | 0.76 | L3MBTL1 (0.55) | TXNRD1L3MBTL1KMT2ARAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627628-B1 | NOVEL ESTERS OF (ACYLOXYMETHYL)ACRYLAMIDE, A PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND THEIR USE AS INHIBITORS OF THE THIOREDOXIN - THIOREDOXIN REDUCTASE SYSTEM | INST CHEMII ORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2015-04-15 | — | — | EP | disclosed |