Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 4/20 | 0.36 |
| ▸ | PER2 | O15055 | 3/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639237 | 0.77 | TRPA1 (0.38) | PARK7PER2CRY2NOTUMALDH1A1 | |
| SCHEMBL16628365 | 0.72 | LMNA (0.46) | CA1CA2GAAHTTMEN1 | |
| SCHEMBL9866424 | 0.68 | CA1 (0.45) | CA1CA2CA7CA9PARK7 | |
| SCHEMBL24376604 | 0.65 | CA1 (0.44) | CA1CA2CA7CA9LRRK2 | |
| SCHEMBL9866562 | 0.61 | NOTUM (0.38) | CA1CA2CA7CA9PARK7 | |
| SCHEMBL16639238 | 0.61 | TRPA1 (0.40) | PARK7PER2NOTUM | |
| SCHEMBL14466675 | 0.60 | PARP1 (0.42) | CA1CA2CA7CA9PARK7 | |
| SCHEMBL25436364 | 0.60 | AR (0.32) | CA1CA2CA7CA9PER2 | |
| SCHEMBL26790924 | 0.58 | CA1 (0.40) | CA1CA2CA7CA9ACHE | |
| SCHEMBL4764513 | 0.57 | PARK7 (0.40) | CA1CA2CA7CA9PARK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860175-B1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE FOR SYNTHESIS THEREOF | TACURION (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2860175-A1 | METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE FOR SYNTHESIS THEREOF | Astellas Pharma Inc. (JP) | 2015-04-15 | — | — | EP | disclosed |