SCHEMBL16639633

SCHEMBL16639633

CC(C)c1ccc2ccc3c(-c4ccc(N(c5ccc(-c6ccccc6)cc5)c5ccccc5-c5ccccc5)cc4)ccc4ccc1c2c43

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP1 O94782 1/20 0.31
WDR48 Q8TAF3 1/20 0.31
PPARG P37231 2/20 0.30
PPARA Q07869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639277 0.94
SCHEMBL16641952 0.89 RXRA (0.31)
SCHEMBL16639634 0.89 RXRA (0.31)
SCHEMBL16639338 0.89 RXRA (0.31)
SCHEMBL16639278 0.86 RXRA (0.31)
SCHEMBL16639279 0.86 RXRA (0.31)
SCHEMBL16639282 0.85 CRHR1 (0.33) PPARG
SCHEMBL16639340 0.85 CYP1A2 (0.35)
SCHEMBL16641958 0.85 TNF (0.32)
SCHEMBL16639637 0.84 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed