Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 2/20 | 0.30 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639318 | 0.95 | HPRT1 (0.33) | RARAUSP1WDR48 | |
| SCHEMBL17573105 | 0.89 | CA12 (0.30) | CA12CA1CA2CA9 | |
| SCHEMBL16641957 | 0.87 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL12433909 | 0.86 | ALDH1A1 (0.34) | RARAMETAP2CA12CA1CA2 | |
| SCHEMBL16639329 | 0.86 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL16639343 | 0.86 | ALOX5 (0.35) | — | |
| SCHEMBL17263989 | 0.86 | RARA (0.30) | RARA | |
| SCHEMBL10354397 | 0.84 | ADRA2A (0.30) | — | |
| SCHEMBL16639307 | 0.84 | HSP90AA1 (0.31) | HSP90AA1 | |
| SCHEMBL16639639 | 0.84 | HSP90AA1 (0.31) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |