Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.53 |
| ▸ | ITGAM | P11215 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177177 | 0.90 | ENPP2 (0.64) | ENPP2PPARGITGB2ITGAMTDP1 | |
| SCHEMBL16644157 | 0.89 | ENPP2 (0.78) | ENPP2HIF1ANITGB2ITGAMTDP1 | |
| SCHEMBL12177487 | 0.89 | ENPP2 (0.66) | ENPP2PPARGHIF1ANITGB2ITGAM | |
| SCHEMBL12177183 | 0.89 | ENPP2 (0.60) | ENPP2PPARGITGB2ITGAMTDP1 | |
| SCHEMBL12177597 | 0.89 | MEN1 (0.61) | ENPP2PPARGHIF1ANITGB2ITGAM | |
| SCHEMBL16687571 | 0.88 | ENPP2 (0.82) | ENPP2ITGB2ITGAMTDP1KDM4E | |
| SCHEMBL17715075 | 0.87 | ENPP2 (0.69) | ENPP2ITGB2ITGAMTDP1KDM4E | |
| SCHEMBL46549 | 0.85 | ITGB2 (0.63) | ENPP2HIF1ANITGB2ITGAMTDP1 | |
| SCHEMBL12177566 | 0.84 | ENPP2 (0.64) | ENPP2ITGB2ITGAMTDP1KDM4E | |
| SCHEMBL16639749 | 0.84 | KMT2A (0.72) | ENPP2ITGB2ITGAMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328105-B2 | Compounds and methods for regulating integrins | ADHAERE PHARMACEUTICALS, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150105435-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRINS | ATEGRIN, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105435-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRINS | ITGA2, ITGB2, ITGA2B | ENPP2 107/4885PPARG 671/4885HIF1AN 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.