SCHEMBL16640320

SCHEMBL16640320

CC(C)c1ccc(-n2c3ccccc3c3ccncc32)nc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
IDO1 P14902 1/20 0.35
GRM4 Q14833 1/20 0.35
MAOA P21397 4/20 0.35
MAOB P27338 4/20 0.35
ACHE P22303 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
ROCK2 O75116 1/20 0.34
TOP2A P11388 1/20 0.34
KDR P35968 1/20 0.34
NFATC1 O95644 1/20 0.33
GSK3B P49841 1/20 0.33
DYRK1A Q13627 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 3/20 0.33
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640315 0.92 MAOA (0.43) MKNK1MKNK2GRM4MAOAMAOB
SCHEMBL16640328 0.90 GRM4 (0.40) MKNK1MKNK2GRM4PTGDR2
SCHEMBL16640317 0.82 KDM4E (0.44) IDO1MAOAMAOBACHEROCK2
SCHEMBL16644612 0.82 AOC3 (0.41) MKNK1MKNK2IDO1MAOAMAOB
SCHEMBL16640319 0.81 GRM4 (0.35) IDO1GRM4MAPTSLC6A2
SCHEMBL16640316 0.81 GRM4 (0.35) GRM4PTGDR2MAPT
SCHEMBL21453891 0.78 MKNK1 (0.35) MKNK1MKNK2IDO1MAOAMAOB
SCHEMBL16644610 0.73 MAOA (0.50) MKNK1MKNK2MAOAMAOBACHE
SCHEMBL16640335 0.73 MAOA (0.47) MAOAMAOBACHETOP2AKDR
SCHEMBL20348119 0.73 MKNK1 (0.44) MKNK1MKNK2IDO1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2020-05-14 US disclosed
US-10566553-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-02-18 US disclosed
US-9947881-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-17 US disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11189808-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 MKNK1 3822/4885MKNK2 3770/4885IDO1 1212/4885
US-10566553-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 MKNK1 3822/4885MKNK2 3770/4885IDO1 1212/4885
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 MKNK1 3822/4885MKNK2 3770/4885IDO1 1212/4885
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 MKNK1 3822/4885MKNK2 3770/4885IDO1 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.