Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640349 | 0.88 | USP2 (0.43) | USP2HTTNCOA1NCOA3DYRK1A | |
| SCHEMBL16640333 | 0.83 | MAPT (0.54) | USP2HTTMAPTTSHRMAPK1 | |
| SCHEMBL16640322 | 0.81 | MAPT (0.41) | USP2HTTNCOA1NCOA3MAPT | |
| SCHEMBL16640338 | 0.81 | DYRK1A (0.50) | USP2HTTNCOA1NCOA3DYRK1A | |
| SCHEMBL16640344 | 0.80 | ACHE (0.46) | USP2HTTNCOA1NCOA3DYRK1A | |
| SCHEMBL2628317 | 0.79 | MAPK14 (0.47) | DYRK1ANFATC1GSK3BL3MBTL1NPC1 | |
| SCHEMBL16640342 | 0.78 | CDK4 (0.41) | USP2HTTNCOA1NCOA3DYRK1A | |
| SCHEMBL29072818 | 0.76 | L3MBTL1 (0.37) | HTTDYRK1ANFATC1GSK3BMAPT | |
| SCHEMBL25955717 | 0.76 | HSP90AA1 (0.37) | DYRK1AGSK3BMAPTL3MBTL1NPC1 | |
| SCHEMBL16640332 | 0.76 | MAPT (0.49) | HTTMAPTTSHRMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11189808-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-11-30 | — | — | US | disclosed |
| US-20200152891-A1 | PLATINUM COMPLEXES AND DEVICES | UNIV ARIZONA STATE (US) | 2020-05-14 | — | — | US | disclosed |
| US-10566553-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-02-18 | — | — | US | disclosed |
| US-9947881-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-01-12 | — | — | US | disclosed |
| US-9385329-B2 | Platinum complexes and devices | Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150105556-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11189808-B2 | Platinum complexes and devices | OXA1L, OCIAD1, OCIAD2 | USP2 4612/4885HTT 2065/4885NCOA1 423/4885 |
| US-10566553-B2 | Platinum complexes and devices | OXA1L, OCIAD1, OCIAD2 | USP2 4612/4885HTT 2065/4885NCOA1 423/4885 |
| US-20200152891-A1 | PLATINUM COMPLEXES AND DEVICES | OXA1L, OCIAD1, OCIAD2 | USP2 4612/4885HTT 2065/4885NCOA1 423/4885 |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | OXA1L, OCIAD1, OCIAD2 | USP2 4612/4885HTT 2065/4885NCOA1 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.