SCHEMBL16640333

SCHEMBL16640333

CC(C)n1c2ccccc2c2ncccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
ATM Q13315 1/20 0.54
LMNA P02545 3/20 0.48
HPGD P15428 1/20 0.48
UTS2R Q9UKP6 1/20 0.45
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
NPY5R Q15761 2/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
NPC1 O15118 2/20 0.42
HSP90AA1 P07900 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
IDO1 P14902 1/20 0.41
HTT P42858 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640322 0.87 MAPT (0.41) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL19579309 0.85 MAPT (0.45) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL16640332 0.84 MAPT (0.49) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL16640326 0.83 USP2 (0.40) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL12110578 0.83 MAPT (0.42) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL16640349 0.83 USP2 (0.43) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL18237637 0.81 MAPT (0.61) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL13316428 0.80 MAPT (0.39) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL16640334 0.79 MAPT (0.54) MAPTTDP1TSHRMAPK1CASP1
SCHEMBL150044 0.78 BCHE (0.59) MAPTTDP1TSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542260-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-01-03 US disclosed
US-20210066613-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-03-04 US disclosed
US-20200203622-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-06-25 US disclosed
US-10644249-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2020-05-05 US disclosed
US-10566553-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-02-18 US disclosed
US-20190267554-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-08-29 US disclosed
US-20190233412-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-08-01 US disclosed
US-20190173020-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-06-06 US disclosed
US-20190173017-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-06-06 US disclosed
US-9947881-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-17 US disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10566553-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 MAPT 1431/4885TDP1 1768/4885TSHR 3038/4885
US-11542260-B2 Composition of matter for use in organic light-emitting diodes CRY2, NDUFV3, SLCO1B3 MAPT 166/4885TDP1 580/4885TSHR 4779/4885
US-20190233412-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, NDUFV3, SLCO1B3 MAPT 166/4885TDP1 580/4885TSHR 4779/4885
US-20190173017-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, ALDH1A2, CYBA MAPT 256/4885TDP1 770/4885TSHR 4747/4885
US-10644249-B2 Composition of matter for use in organic light-emitting diodes NDUFV3, SLCO1B3, CRY2 MAPT 177/4885TDP1 1242/4885TSHR 4737/4885
US-20200203622-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES NDUFV3, NDUFV2, CRY2 MAPT 275/4885TDP1 1384/4885TSHR 4573/4885
US-20190267554-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES NDUFV3, SLCO1B3, CRY2 MAPT 177/4885TDP1 1242/4885TSHR 4737/4885
US-20190173020-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, ALDH1A2, CYBA MAPT 256/4885TDP1 770/4885TSHR 4747/4885
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 MAPT 1431/4885TDP1 1768/4885TSHR 3038/4885
US-20210066613-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CYBA, NDUFV3 MAPT 152/4885TDP1 816/4885TSHR 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.