SCHEMBL11941322

SCHEMBL11941322

COCCOC(=O)c1ccc(C(=O)OCCO)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
CYP3A4 P08684 2/20 0.52
ABCB11 O95342 1/20 0.52
ADRA2B P18089 1/20 0.52
OPRD1 P41143 1/20 0.52
SCN5A Q14524 1/20 0.52
ESR1 P03372 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
KDR P35968 1/20 0.50
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17299367 1.00 TSHR (0.56) TSHRCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL17299369 1.00 TSHR (0.56) TSHRCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL9969969 0.92 TSHR (0.64) TSHRCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL19235060 0.90 TDP1 (0.54) TSHRCYP3A4ESR1TDP1ALDH1A1
SCHEMBL13292517 0.90 TDP1 (0.54) TSHRCYP3A4ESR1TDP1ALDH1A1
SCHEMBL26453328 0.90 TDP1 (0.54) TSHRCYP3A4ESR1TDP1ALDH1A1
SCHEMBL26378 0.88 TDP1 (0.56) TSHRCYP3A4ESR1TDP1ALDH1A1
SCHEMBL29321155 0.87 TSHR (0.49) TSHRCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL16640624 0.86 MAPT (0.60) TSHRCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL9928660 0.86 CYP3A4 (0.66) TSHRCYP3A4ABCB11ADRA2BOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023079280-A1 CONDUCTIVE BINDER MATERIALS DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2023-05-11 WO disclosed
US-10005068-B2 Catalyst and manufacturing method thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-06-26 US disclosed
US-20170349744-A1 POLYESTER ELASTOMER INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-12-07 US disclosed
US-20170087536-A1 CATALYST AND MANUFACTURING METHOD THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-03-30 US disclosed
US-9545617-B2 Catalyst and manufacturing method thereof and method for manufacturing hydrogenated bisphenol A or derivatives thereof using the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-01-17 US disclosed
US-9458354-B2 Polyurethane dispersions and methods of making and using same Resinate Technologies, Inc. (US) 2016-10-04 US disclosed
US-9422398-B2 Copolymer, and method for preparing a monomer used to form the copolymer INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-08-23 US disclosed
US-20160158731-A1 CATALYST AND MANUFACTURING METHOD THEREOF AND METHOD FOR MANUFACTURING HYDROGENATED BISPHENOL A OR DERIVATIVES THEREOF USING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-06-09 US disclosed
US-20150344414-A1 COPOLYMER, AND METHOD FOR PREPARING A MONOMER USED TO FORM THE COPOLYMER INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-12-03 US disclosed
US-20140107374-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME FELICE KRISTOPHER M (US) 2014-04-17 US disclosed
US-20140107374-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME FELICE KRISTOPHER M (US) 2014-04-17 US disclosed
US-20120259061-A1 Polyurethane Dispersions and Methods of Making and Using Same RESINATE MATERIALS GROUP, INC. 2012-10-11 US disclosed
US-20120190800-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME FELICE KRISTOPHER M (US) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107374-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME PIGO, ESD, FTO TSHR 636/4885CYP3A4 1358/4885ABCB11 1513/4885
US-20160158731-A1 CATALYST AND MANUFACTURING METHOD THEREOF AND METHOD FOR MANUFACTURING HYDROGENATED BISPHENOL A OR DERIVATIVES THEREOF USING THE SAME XDH, HAX1, MLX TSHR 1529/4885CYP3A4 284/4885ABCB11 1303/4885
US-20150344414-A1 COPOLYMER, AND METHOD FOR PREPARING A MONOMER USED TO FORM THE COPOLYMER CCNH, PAM, POLH TSHR 4303/4885CYP3A4 2182/4885ABCB11 4485/4885
US-20170087536-A1 CATALYST AND MANUFACTURING METHOD THEREOF MLX, HAX1, XDH TSHR 4119/4885CYP3A4 793/4885ABCB11 1595/4885
US-20120190800-A1 FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME PIGO, ESD, FTO TSHR 636/4885CYP3A4 1358/4885ABCB11 1513/4885
US-10005068-B2 Catalyst and manufacturing method thereof MLX, HAX1, XDH TSHR 4119/4885CYP3A4 793/4885ABCB11 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.