Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.37 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12896205 | 0.84 | CYP2D6 (0.51) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL6801407 | 0.74 | KDM4E (0.31) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL6855483 | 0.74 | KDM4E (0.31) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL20832962 | 0.74 | CYP2C19 (0.56) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL20832965 | 0.74 | CYP2C19 (0.56) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL25337905 | 0.74 | CYP2C19 (0.56) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL22259825 | 0.74 | CYP2C19 (0.56) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL13894842 | 0.73 | GBA1 (0.34) | GBA1 | |
| SCHEMBL10326842 | 0.71 | CYP2D6 (0.61) | MAPK1CYP2D6KDM4ENPC1CYP1A2 | |
| SCHEMBL10326922 | 0.71 | CYP2D6 (0.61) | MAPK1CYP2D6KDM4ENPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701601-B2 | Optically active axially chiral alpha-allenic alcohol, synthesis method and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-07-11 | — | — | US | disclosed |
| US-20150105567-A1 | OPTICALLY ACTIVE AXIALLY CHIRAL ALPHA-ALLENIC ALCOHOL, SYNTHESIS METHOD AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105567-A1 | OPTICALLY ACTIVE AXIALLY CHIRAL ALPHA-ALLENIC ALCOHOL, SYNTHESIS METHOD AND USE THEREOF | ALDH18A1, ADH1C, ADH1A | MAPK1 2277/4885CYP2D6 1087/4885KDM4E 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.