Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326922 | 0.85 | CYP2D6 (0.61) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL10326842 | 0.85 | CYP2D6 (0.61) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL5050029 | 0.85 | CYP2D6 (0.61) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL16640673 | 0.84 | MAPK1 (0.39) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL14505930 | 0.78 | CYP2D6 (0.51) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL8621668 | 0.73 | CYP2D6 (0.79) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL6295242 | 0.73 | CYP2D6 (0.79) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL5054811 | 0.73 | CYP2D6 (0.79) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL10248547 | 0.72 | CYP2D6 (0.42) | CYP2D6MAPK1KDM4ENPC1CYP1A2 | |
| SCHEMBL6801407 | 0.72 | KDM4E (0.31) | CYP2D6MAPK1KDM4ENPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701601-B2 | Optically active axially chiral alpha-allenic alcohol, synthesis method and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-07-11 | — | — | US | disclosed |
| US-9701601-B2 | Optically active axially chiral alpha-allenic alcohol, synthesis method and use thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-07-11 | — | — | US | disclosed |
| US-9388205-B2 | Ni complex and its derivatives, producing method, and the use thereof as an antioxidant | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2016-07-12 | — | — | US | disclosed |
| US-20150105567-A1 | OPTICALLY ACTIVE AXIALLY CHIRAL ALPHA-ALLENIC ALCOHOL, SYNTHESIS METHOD AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-04-16 | — | — | US | disclosed |
| US-20150105567-A1 | OPTICALLY ACTIVE AXIALLY CHIRAL ALPHA-ALLENIC ALCOHOL, SYNTHESIS METHOD AND USE THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-04-16 | — | — | US | disclosed |
| US-20140051859-A1 | NOVEL NI COMPLEX AND ITS DERIVATIVES, PRODUCING METHOD, AND THE USE THEREOF AS AN ANTIOXIDANT | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2014-02-20 | — | — | US | disclosed |
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | UNIVERSITETET I OSLO (NO) | 2011-02-10 | — | — | US | disclosed |
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | UNIVERSITETET I OSLO (NO) | 2011-02-10 | — | — | US | disclosed |
| WO-2009087177-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | UNIVERSITETET I OSLO (NO) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034654-A1 | POLYMER ORGANOCATALYST AND PREPARATION PROCESS | HRH3, HRH4, H1-3 | CYP2D6 1481/4885MAPK1 2934/4885KDM4E 2335/4885 |
| US-20140051859-A1 | NOVEL NI COMPLEX AND ITS DERIVATIVES, PRODUCING METHOD, AND THE USE THEREOF AS AN ANTIOXIDANT | SOD1, SOD3, LPO | CYP2D6 502/4885MAPK1 2477/4885KDM4E 3566/4885 |
| US-20150105567-A1 | OPTICALLY ACTIVE AXIALLY CHIRAL ALPHA-ALLENIC ALCOHOL, SYNTHESIS METHOD AND USE THEREOF | ALDH18A1, ADH1C, ADH1A | CYP2D6 1087/4885MAPK1 2277/4885KDM4E 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.