Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SLC22A12 | Q96S37 | 12/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.45 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791538 | 0.76 | ALDH1A1 (1.00) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3553632 | 0.76 | SLC16A3 (0.68) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3726033 | 0.76 | SLC22A12 (0.65) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3566896 | 0.76 | SLC16A3 (0.61) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3563709 | 0.74 | MEN1 (0.57) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3555598 | 0.73 | PKLR (0.58) | MEN1ALDH1A1KMT2ASLC22A12ALKBH2 | |
| SCHEMBL27535606 | 0.72 | MEN1 (0.54) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL6541948 | 0.71 | KMT2A (0.80) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 | |
| SCHEMBL3720283 | 0.71 | SLC22A12 (0.62) | MEN1ALDH1A1KMT2ASLC22A12ALKBH2 | |
| SCHEMBL2668794 | 0.70 | MEN1 (0.61) | MEN1ALDH1A1KMT2ASLC22A12BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |