Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 7/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.54 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724899 | 0.80 | FABP4 (0.59) | ALDH1A1KMT2AFABP4ACLYPTK2B | |
| SCHEMBL3720283 | 0.80 | SLC22A12 (0.62) | SLC22A12MEN1ALDH1A1KMT2AFABP4 | |
| SCHEMBL27791538 | 0.78 | ALDH1A1 (1.00) | SLC22A12MEN1ALDH1A1KMT2AFABP4 | |
| SCHEMBL16645353 | 0.76 | MEN1 (0.61) | SLC22A12MEN1ALDH1A1KMT2APTK2B | |
| SCHEMBL3553632 | 0.75 | SLC16A3 (0.68) | SLC22A12MEN1ALDH1A1KMT2AALKBH2 | |
| SCHEMBL3562163 | 0.75 | SLC16A3 (0.71) | SLC22A12MEN1ALDH1A1KMT2AALKBH2 | |
| SCHEMBL3566896 | 0.75 | SLC16A3 (0.61) | SLC22A12MEN1ALDH1A1KMT2AALKBH2 | |
| SCHEMBL3557901 | 0.74 | SLC16A3 (0.64) | SLC22A12MEN1ALDH1A1KMT2AALKBH2 | |
| SCHEMBL3555598 | 0.74 | PKLR (0.58) | SLC22A12MEN1ALDH1A1KMT2APTK2B | |
| SCHEMBL27681 | 0.74 | ALDH1A1 (0.61) | SLC22A12MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126922-A1 | BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010126922-A1 | BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |