Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16646117 | 0.89 | ALOX12 (0.66) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL16646174 | 0.81 | ALOX12 (0.50) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL16646116 | 0.79 | ALOX12 (0.40) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL18356879 | 0.78 | ALOX12 (0.81) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL26545970 | 0.78 | ALOX12 (0.51) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL12534309 | 0.69 | LMNA (0.51) | ALDH1A1GAALMNAMAPK1PKM | |
| SCHEMBL18560178 | 0.69 | ALDH1A1 (0.47) | ALDH1A1GAAMAPK1PKMKMT2A | |
| SCHEMBL11510283 | 0.68 | MEN1 (0.59) | ALOX12ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL18356429 | 0.68 | ALOX12 (1.00) | ALOX12ALDH1A1GAALMNAMAPK1 | |
| SCHEMBL26545984 | 0.67 | ALOX12 (0.65) | ALOX12ALDH1A1GAALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054662-A1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2015-04-16 | — | — | WO | disclosed |