Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16442683 | 0.91 | RECQL (0.42) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9290096 | 0.91 | ESR1 (0.48) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL16648182 | 0.90 | ESR1 (0.41) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9288711 | 0.90 | PTGER4 (0.46) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9288673 | 0.89 | ESR1 (0.45) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9288680 | 0.88 | PTGER4 (0.41) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL21891300 | 0.88 | PTGER4 (0.41) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9288668 | 0.87 | ESR1 (0.43) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9290148 | 0.86 | PTGER4 (0.41) | RECQLESR1ESR2PTGER4RPS6KB1 | |
| SCHEMBL9288338 | 0.86 | ESR1 (0.46) | RECQLESR1ESR2PTGER4RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055303-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-02 | — | — | EP | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| WO-2015051869-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, LEF1, KCNC1 | RECQL 1804/4885ESR1 18/4885ESR2 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.