Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12567850 | 0.88 | ALOX5 (0.43) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL22736407 | 0.84 | ESR1 (0.44) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL12349150 | 0.83 | GSR (0.43) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL16648246 | 0.83 | ESR1 (0.42) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL18031683 | 0.82 | ESR1 (0.44) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL16648187 | 0.82 | ESR1 (0.44) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL12567977 | 0.82 | ALOX5 (0.44) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL23169659 | 0.81 | ESR1 (0.46) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL12349385 | 0.81 | ESR2 (0.52) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL23169660 | 0.81 | ESR1 (0.44) | ESR1ESR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055303-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-02 | — | — | EP | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| WO-2015051869-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160248023-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, LEF1, KCNC1 | ESR1 18/4885ESR2 99/4885KDM4E 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.