SCHEMBL16648709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16648729	0.86	DRD2 (0.52)	PARP1LCATUSP30
	SCHEMBL16648802	0.84	CHRNB2 (0.50)	LCATUSP30
	SCHEMBL16664264	0.83	LCAT (0.46)	PARP1LCATJAK2JAK1HSD11B1
	SCHEMBL16648757	0.83	LCAT (0.46)	PARP1LCATUSP30CHEK1
	SCHEMBL16648547	0.83	ALDH1A1 (0.48)	LCATKDM4ETP53HRH3
	SCHEMBL16648641	0.82	MAPT (0.46)	LCATTP53HRH3
	SCHEMBL16648971	0.81	LCAT (0.48)	PARP1LCATUSP30HRH3AVPR1A
	SCHEMBL16648839	0.79	LCAT (0.46)	LCATKDM4ETP53MAP4K1
	SCHEMBL16648917	0.77	LCAT (0.55)	LCATCHEK1
	SCHEMBL16648460	0.77	LCAT (0.53)	LCAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.