Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406998 | 0.82 | PBRM1 (0.34) | PBRM1 | |
| SCHEMBL13837016 | 0.77 | KMT2A (0.31) | — | |
| SCHEMBL16649918 | 0.74 | KDM4E (0.32) | KDM4E | |
| SCHEMBL5800279 | 0.72 | CES2 (0.39) | PBRM1 | |
| SCHEMBL16650033 | 0.71 | CDC7 (0.32) | — | |
| SCHEMBL12095025 | 0.70 | MCL1 (0.30) | — | |
| SCHEMBL15511847 | 0.70 | CASP1 (0.33) | — | |
| SCHEMBL8676513 | 0.69 | PBRM1 (0.43) | PBRM1 | |
| SCHEMBL12497303 | 0.67 | CDC7 (0.34) | PBRM1 | |
| SCHEMBL2842495 | 0.66 | POLB (0.42) | PBRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |