Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 10/20 | 0.41 |
| ▸ | RAB9A | P51151 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665030 | 0.96 | RAB9A (0.48) | HPGDSNPC1RAB9APOLBKMT2A | |
| SCHEMBL8771289 | 0.78 | RAB9A (0.48) | HPGDSNPC1RAB9APOLBKMT2A | |
| SCHEMBL1665072 | 0.75 | HPGDS (0.48) | HPGDSNPC1RAB9AKMT2AMAPT | |
| SCHEMBL1664840 | 0.74 | HPGDS (0.61) | HPGDSNPC1RAB9AKMT2AMAPT | |
| SCHEMBL1663295 | 0.73 | HPGDS (0.63) | HPGDSNPC1RAB9AKMT2AMAPT | |
| SCHEMBL8769706 | 0.73 | RAB9A (0.58) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL1664351 | 0.73 | HPGDS (0.62) | HPGDSNPC1RAB9AKMT2AMAPT | |
| SCHEMBL1664007 | 0.73 | RAB9A (0.51) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL1664676 | 0.72 | HPGDS (0.54) | HPGDSNPC1RAB9APOLBKMT2A | |
| SCHEMBL1665239 | 0.72 | SMN1; SMN2 (0.46) | HPGDSNPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |