Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 15/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665102 | 0.96 | HPGDS (0.51) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1664077 | 0.85 | HPGDS (0.49) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1664779 | 0.84 | RAB9A (0.61) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1663295 | 0.84 | HPGDS (0.63) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1666278 | 0.83 | HPGDS (0.60) | HPGDSNPC1RAB9A | |
| SCHEMBL1664351 | 0.83 | HPGDS (0.62) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21254882 | 0.83 | HPGDS (0.39) | HPGDSKMT2ANPC1RAB9A | |
| SCHEMBL1664840 | 0.82 | HPGDS (0.61) | HPGDSKMT2ANPC1RAB9AMAPT | |
| SCHEMBL1664080 | 0.81 | HPGDS (0.46) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1666281 | 0.80 | HPGDS (0.56) | HPGDSKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |