Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888140 | 0.91 | CYP1A2 (0.40) | ALDH1A1TSHRCYP3A4POLBTDP1 | |
| SCHEMBL1185484 | 0.85 | TSHR (0.60) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL12090352 | 0.77 | TSHR (0.60) | ALDH1A1TSHRCYP3A4HSD17B10KDM4E | |
| SCHEMBL2064927 | 0.76 | FBP1 (0.46) | TSHRCYP3A4TDP1MAPTMAPK1 | |
| SCHEMBL1665662 | 0.74 | ALOX15 (0.43) | ALDH1A1TSHRCYP3A4HTTCES2 | |
| SCHEMBL888064 | 0.74 | CYP1A2 (0.44) | ALDH1A1TSHRTDP1SMN1; SMN2MAPK1 | |
| SCHEMBL14676339 | 0.74 | CYP1A2 (0.40) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL1620602 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4RECQLHTT | |
| SCHEMBL23257600 | 0.73 | MAPT (0.46) | ALDH1A1TSHRCYP3A4RECQLHTT | |
| SCHEMBL31039440 | 0.73 | MAPT (0.46) | ALDH1A1TSHRCYP3A4RECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |