Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488281 | 0.80 | POLB (0.59) | POLBALDH1A1PKMCYP2A6CYP3A4 | |
| SCHEMBL433371 | 0.79 | POLB (1.00) | POLBALDH1A1PKMCYP3A4PI4KA | |
| SCHEMBL30385755 | 0.79 | HTT (0.44) | POLBALDH1A1CYP2A6CYP11B2CYP3A4 | |
| SCHEMBL25417972 | 0.77 | CYP2A6 (0.46) | POLBALDH1A1CYP2A6CYP11B2CYP3A4 | |
| SCHEMBL2691172 | 0.77 | CYP2A6 (0.49) | ALDH1A1CYP2A6CYP11B2CYP3A4CYP2E1 | |
| SCHEMBL6086847 | 0.76 | CYP11B2 (0.46) | CYP2A6CYP11B2CYP3A4CYP2E1HTT | |
| SCHEMBL1491136 | 0.75 | POLB (0.69) | POLBALDH1A1PKMCYP3A4MAPT | |
| SCHEMBL17457925 | 0.74 | CYP2A6 (0.47) | CYP2A6CYP11B2CYP3A4CYP2E1HTT | |
| SCHEMBL30235475 | 0.74 | F7 (0.47) | ALDH1A1CYP2A6CYP11B2CYP3A4HTT | |
| SCHEMBL14955293 | 0.73 | CA12 (0.51) | ALDH1A1CYP2A6CYP11B2CYP3A4CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906029-A1 | INHIBITORS OF MENIN-MLL INTERACTION | Biomea Fusion, LLC (US) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020142559-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BIOMEA FUSION, LLC (US) | 2020-07-09 | — | — | WO | disclosed |
| CN-105828610-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105744838-B | Heterocyclic compound as agricultural chemicals | 拜耳作物科学股份公司 | 2017-12-08 | — | — | CN | disclosed |
| US-9523100-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2016-07-21 | — | — | US | disclosed |
| US-9295260-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| CN-101679287-B | Nicotinic acetylcholine receptor modulators | SIENA BIOTECH SPA | 2013-03-27 | — | — | CN | disclosed |
| CN-101679287-A | nicotinic acetylcholine receptor modulators | SIENA BIOTECH SPA | 2010-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, RDX, PRDX1 | POLB 4565/4885ALDH1A1 3417/4885PKM 895/4885 |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, RDX, CHRM2 | POLB 4392/4885ALDH1A1 3453/4885PKM 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.