SCHEMBL1665301

SCHEMBL1665301

Nc1ncnc2ncn(CO)c12

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.69
ADORA1 P30542 4/20 0.50
EGFR P00533 1/20 0.47
SRC P12931 1/20 0.47
KDR P35968 1/20 0.47
TEK Q02763 1/20 0.47
PIK3CD O00329 2/20 0.41
AHCY P23526 7/20 0.40
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39
PI4KB Q9UBF8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815870 0.86 ADORA2A (0.71) ADORA2AADORA1EGFRSRCKDR
SCHEMBL1665392 0.83 ADORA2A (0.71) ADORA2AADORA1EGFRSRCKDR
SCHEMBL5801729 0.81 ADORA2A (1.00) ADORA2AADORA1EGFRSRCKDR
SCHEMBL6690627 0.79 ADORA2A (0.56) ADORA2AADORA1EGFRSRCKDR
SCHEMBL4541360 0.77 ADORA2A (0.62) ADORA2AADORA1EGFRSRCKDR
SCHEMBL3306409 0.77 AHCY (0.65) ADORA2AADORA1EGFRSRCKDR
SCHEMBL4343213 0.75 ADORA2A (0.60) ADORA2AADORA1EGFRSRCKDR
SCHEMBL9255634 0.73 ADORA2A (0.49) ADORA2AADORA1EGFRSRCKDR
Hydrochloric Acid SCHEMBL9778348 0.73 ADORA2A (0.75) ADORA2AADORA1KDR
Hydrochloric Acid SCHEMBL9778362 0.73 ADORA2A (0.75) ADORA2AADORA1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260043083-A1 DNA-BARCODED ANTIGEN MULTIMERS AND METHODS OF USE THEREOF UNIV TEXAS (US) 2026-02-12 US disclosed
EP-4276198-B1 NUCLEIC ACID SYNTHESIS AND SEQUENCING USING TETHERED NUCLEOSIDE TRIPHOSPHATES UNIV CALIFORNIA (US) 2025-11-26 EP disclosed
US-12435356-B2 Target reporter constructs and uses thereof REDVAULT BIOSCIENCES, LP (US) 2025-10-07 US disclosed
US-20240401099-A1 Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-05 US disclosed
US-20240368682-A1 SYSTEMS AND METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS REDVAULT BIOSCIENCES LP (US) 2024-11-07 US disclosed
US-20240191298-A1 DNA-BARCODED ANTIGEN MULTIMERS AND METHOD OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-06-13 US disclosed
EP-4372102-A2 TARGET REPORTER CONSTRUCTS AND USES THEREOF RedVault Biosciences, LP (US) 2024-05-22 EP disclosed
US-20240140977-A1 REVERSIBLE TERMINATORS ANSA BIOTECHNOLOGIES, INC. 2024-05-02 US disclosed
EP-3464628-B1 TARGET REPORTER CONSTRUCTS AND USES THEREOF REDVAULT BIOSCIENCES LP (US) 2024-01-31 EP disclosed
US-20240026436-A1 METHODS AND COMPOSITIONS FOR THE AMPLIFICATION OF MRNA BAYLOR COLLEGE OF MEDICINE (US) 2024-01-25 US disclosed
EP-2755984-A1 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING Lasergen, Inc. (US) 2014-07-23 EP disclosed
US-20140051848-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2014-02-20 US disclosed
US-8497360-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2013-07-30 US disclosed
US-20130122489-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING AGILENT TECHNOLOGIES, INC. 2013-05-16 US disclosed
WO-2013040257-A1 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING LASERGEN, INC. (US) 2013-03-21 WO disclosed
US-20130035237-A1 Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing AGILENT TECHNOLOGIES, INC. 2013-02-07 US disclosed
US-8148503-B2 Nucleotides and nucleosides and methods for their use in DNA sequencing LASERGEN, INC. (US) 2012-04-03 US disclosed
EP-2307565-A2 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING Lasergen, Inc. (US) 2011-04-13 EP disclosed
US-20100041041-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2010-02-18 US disclosed
WO-2009152353-A2 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING LASERGEN, INC. (US) 2009-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041041-A1 NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING UNG, NT5C2, NT5E ADORA2A 274/4885ADORA1 251/4885EGFR 2738/4885
US-20240401099-A1 Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates RNGTT, DNTT, TYMP ADORA2A 398/4885ADORA1 377/4885EGFR 3630/4885
US-20260043083-A1 DNA-BARCODED ANTIGEN MULTIMERS AND METHODS OF USE THEREOF HLA-DRB1, MICA, CD74 ADORA2A 2764/4885ADORA1 2754/4885EGFR 2097/4885
US-20240140977-A1 REVERSIBLE TERMINATORS RNGTT, TYMP, TYMS ADORA2A 2953/4885ADORA1 3082/4885EGFR 4523/4885
US-20130035237-A1 Nucleotides and Nucleosides and Methods for their Use in DNA Sequencing UNG, NT5C2, NT5E ADORA2A 274/4885ADORA1 251/4885EGFR 2738/4885
US-20130122489-A1 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING RNGTT, NT5C3B, NSUN2 ADORA2A 1117/4885ADORA1 1196/4885EGFR 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.