Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15099757 | 0.89 | TBK1 (0.33) | TBK1FFAR1ALDH2 | |
| SCHEMBL15093458 | 0.84 | ALDH2 (0.32) | PSIP1ALDH2 | |
| SCHEMBL15093673 | 0.83 | TBK1 (0.34) | TBK1FFAR1PTGES | |
| SCHEMBL15093208 | 0.79 | PSIP1 (0.43) | PSIP1 | |
| SCHEMBL1699368 | 0.79 | CYP3A4 (0.43) | TBK1PSIP1ALDH2 | |
| SCHEMBL15093274 | 0.77 | CYP3A4 (0.41) | PSIP1 | |
| SCHEMBL15093540 | 0.77 | PSIP1 (0.38) | PSIP1 | |
| SCHEMBL1699460 | 0.76 | CYP3A4 (0.42) | PSIP1FFAR1 | |
| SCHEMBL15099756 | 0.75 | ALDH2 (0.31) | ALDH2 | |
| SCHEMBL15093639 | 0.74 | CYP3A4 (0.63) | PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284323-B2 | Naphthalene acetic acid derivatives against HIV infection | GILEAD SCIENCES, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20150111891-A1 | NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111891-A1 | NAPHTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION | NFATC1, ACIN1, NAAA | TBK1 1541/4885PSIP1 3735/4885FFAR1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.