Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24884734 | 0.73 | MAOB (0.42) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL16654485 | 0.69 | MAPT (0.60) | KDM4EALDH1A1HSD17B10CYP3A4GAA | |
| SCHEMBL3887841 | 0.69 | KDR (0.54) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8183283 | 0.68 | CA2 (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL6833560 | 0.68 | MCL1 (0.74) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20274266 | 0.67 | MEN1 (0.39) | AKR1B1THRBMEN1KMT2A | |
| SCHEMBL24884726 | 0.67 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL7963459 | 0.67 | ALDH1A1 (0.45) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8374891 | 0.66 | HSD17B3 (0.61) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11435154 | 0.66 | MCL1 (0.59) | MCL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |