Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15727580 | 0.77 | KIF11 (0.40) | MEN1KMT2AAKR1B1KIF11EPHX2 | |
| SCHEMBL22044994 | 0.74 | EPHX2 (0.47) | AKR1B1KIF11EPHX2GRM4PIM1 | |
| SCHEMBL16629667 | 0.73 | PON1 (0.58) | MEN1KMT2A | |
| SCHEMBL8183283 | 0.70 | CA2 (0.54) | THRB | |
| SCHEMBL21116465 | 0.69 | TP53 (0.46) | KIF11EPHX2 | |
| SCHEMBL16441224 | 0.68 | EPHX2 (0.42) | KIF11EPHX2PIM1PIM2HRH4 | |
| SCHEMBL18015728 | 0.68 | EPHX2 (0.54) | KIF11EPHX2GRM4 | |
| SCHEMBL20893357 | 0.67 | HIF1A (0.71) | HIF1A | |
| SCHEMBL16654745 | 0.67 | MCL1 (0.46) | MEN1KMT2AAKR1B1THRB | |
| SCHEMBL24884734 | 0.67 | MAOB (0.42) | KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |