Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954022 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MEN1POLBKMT2AALOX15 | |
| SCHEMBL10372679 | 0.74 | POLB (0.40) | ALDH1A1MEN1POLBKMT2AEDNRB | |
| SCHEMBL4685836 | 0.73 | ALDH1A1 (0.46) | ALDH1A1PARP3MEN1POLBKMT2A | |
| SCHEMBL6080166 | 0.71 | EDNRB (0.41) | ALDH1A1MEN1POLBKMT2AEDNRB | |
| SCHEMBL3616941 | 0.70 | MAOA (0.36) | MEN1KMT2AMAOAMAOB | |
| SCHEMBL5223009 | 0.69 | HTR6 (0.42) | ALDH1A1HDAC8MAOB | |
| SCHEMBL6607488 | 0.68 | ALDH1A1 (0.39) | ALDH1A1IDO1PARP3MEN1POLB | |
| SCHEMBL2933046 | 0.68 | GABRP (0.37) | ALDH1A1MEN1POLBKMT2AALOX15 | |
| SCHEMBL6314591 | 0.68 | MEN1 (0.40) | ALDH1A1IDO1PARP3MEN1POLB | |
| SCHEMBL3421519 | 0.67 | ALDH1A1 (0.36) | ALDH1A1MEN1POLBKMT2AEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057586-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015058160-A1 | BROMODOMAIN INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2015-04-23 | — | — | WO | disclosed |