SCHEMBL16656190

SCHEMBL16656190

Cc1ccc(-c2ccc3c(n2)-c2nc(C)ccc2C(=O)C3=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
NSD2 O96028 2/20 0.42
G6PD P11413 2/20 0.42
DNMT1 P26358 2/20 0.42
HPGDS O60760 1/20 0.42
TP53 P04637 1/20 0.42
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
AGTR1 P30556 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
LMNA P02545 1/20 0.41
AR P10275 2/20 0.36
GRM2 Q14416 1/20 0.35
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656347 0.83 NSD2 (0.36) S100A4NPC1RAB9ANSD2G6PD
SCHEMBL3722975 0.82 S100A4 (0.59) S100A4RAB9ANSD2G6PDDNMT1
Water SCHEMBL10372295 0.80 NSD2 (0.58) S100A4RAB9ANSD2G6PDDNMT1
SCHEMBL16601685 0.75 MAPT (0.50) NPC1RAB9AHPGDSPKMSMN1; SMN2
SCHEMBL31460555 0.74 RAB9A (0.48) NPC1RAB9APKMAGTR1SMN1; SMN2
SCHEMBL31393223 0.74 KMT2A (0.44) NPC1RAB9AHPGDSTP53PKM
SCHEMBL31393236 0.69 TDP1 (0.55) NPC1RAB9ATP53PKMMAPK1
SCHEMBL31393252 0.69 TDP1 (0.55) NPC1RAB9ATP53PKMMAPK1
SCHEMBL16656191 0.69 NSD2 (0.68) S100A4NSD2G6PDDNMT1MEN1
SCHEMBL31393229 0.68 ALDH1A3 (0.46) NPC1RAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed