SCHEMBL16656192

SCHEMBL16656192

CCC(CC(C)C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C)C3=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
HPGD P15428 3/20 0.37
KEAP1 Q14145 3/20 0.37
NFE2L2 Q16236 3/20 0.37
KDM4E B2RXH2 3/20 0.37
USP2 O75604 2/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ATM Q13315 1/20 0.37
CASP3 P42574 1/20 0.37
TERT O14746 5/20 0.37
POLB P06746 1/20 0.36
PRMT1 Q99873 1/20 0.36
TLR9 Q9NR96 1/20 0.34
RGS12 O14924 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656165 0.90 CASP3 (0.41) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL16656193 0.89 MEN1 (0.36) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL24976834 0.84 MEN1 (0.40) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL16601633 0.83 PRMT1 (0.39) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL12382279 0.82 TERT (0.41) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL11938187 0.81 PRMT1 (0.41) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL10018480 0.81 PRMT1 (0.40) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL18348919 0.78 MEN1 (0.43) ALDH1A1MEN1KMT2AHPGDKEAP1
SCHEMBL15764213 0.78 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AKDM4EL3MBTL1
SCHEMBL12382277 0.78 TERT (0.38) ALDH1A1MEN1KMT2AHPGDKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed