SCHEMBL16656203

SCHEMBL16656203

CCCCCC(C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCSCCO)C3=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RGS12 O14924 2/20 0.44
HTT P42858 2/20 0.44
ALDH1A1 P00352 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
PABPC1 P11940 1/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TERT O14746 6/20 0.36
DYRK3 O43781 1/20 0.36
RPS6KB1 P23443 1/20 0.36
EPHA2 P29317 1/20 0.36
FLT4 P35916 1/20 0.36
CSNK2A1 P68400 1/20 0.36
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12132256 0.81 TDP1 (0.40) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL18351285 0.80 SMN1; SMN2 (0.36) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL13259509 0.80 MEN1 (0.46) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL16656199 0.80 KDM4E (0.46) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL10018481 0.79 SHMT2 (0.39) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL15764209 0.79 KDM4E (0.44) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL18351289 0.79 KMT2A (0.38) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL18348922 0.78 TERT (0.39) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL13259586 0.77 SHMT2 (0.37) KDM4EMEN1KMT2ARGS12HTT
SCHEMBL412569 0.77 SHMT2 (0.37) KDM4EMEN1KMT2ARGS12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed