Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.56 |
| ▸ | ITGAL | P20701 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233981 | 1.00 | ALOX15 (0.63) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| SCHEMBL12950374 | 1.00 | ALOX15 (0.63) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| SCHEMBL13594307 | 0.90 | ECE1 (0.64) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| SCHEMBL7283518 | 0.90 | ECE1 (0.64) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| SCHEMBL19296166 | 0.89 | KDM4E (0.63) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| Abrine (L) SCHEMBL18777 | 0.89 | ALOX15 (0.70) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| Abrine SCHEMBL29404678 | 0.89 | ALOX15 (0.70) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| Abrine SCHEMBL161767 | 0.89 | ALOX15 (0.70) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| SCHEMBL14595060 | 0.89 | KDM4E (0.63) | ALOX15KDM4EMAPTPOLBAPAF1 | |
| Abrine (L) SCHEMBL29585648 | 0.89 | ALOX15 (0.70) | ALOX15KDM4EMAPTPOLBAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012603-B2 | Peptides that block the binding of IgG to FcRn | BIOGEN IDEC HEMOPHILIA INC. (US) | 2015-04-21 | — | — | US | disclosed |