Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 3/20 | 0.59 |
| ▸ | MMP8 | P22894 | 3/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 5/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.56 |
| ▸ | ITGAL | P20701 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595060 | 1.00 | KDM4E (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL26312404 | 0.89 | ALOX15 (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL12950374 | 0.89 | ALOX15 (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL13233981 | 0.89 | ALOX15 (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL9026907 | 0.89 | ECE1 (0.65) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL16656706 | 0.89 | ALOX15 (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL13176572 | 0.87 | TACR1 (0.67) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL5747459 | 0.87 | TACR1 (0.67) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL170877 | 0.87 | KDM4E (0.69) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL170878 | 0.87 | KDM4E (0.69) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | UNIV NEW YORK (US) | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | KDM4E 1733/4885MAPT 4097/4885APAF1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.