Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5875070 | 0.90 | NPC1 (0.44) | TSHRALDH1A1NPC1HSD17B10RAB9A | |
| SCHEMBL5874855 | 0.86 | RXFP1 (0.47) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL8319149 | 0.86 | TSHR (0.37) | TSHRALDH1A1NPC1CYP3A4HSD17B10 | |
| SCHEMBL11420640 | 0.85 | HPGD (0.33) | TSHRALDH1A1NPC1TDP1HSD17B10 | |
| SCHEMBL11420642 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1ALOX15L3MBTL1HSD17B10 | |
| SCHEMBL5874810 | 0.79 | NPC1 (0.55) | TSHRALDH1A1NPC1ALOX15TDP1 | |
| Morpholine Salicylate SCHEMBL24540 | 0.77 | RAB9A (0.59) | TSHRALDH1A1NPC1ALOX15TDP1 | |
| SCHEMBL4451473 | 0.77 | POLB (0.54) | ALDH1A1HPGDLMNAKMT2AHTT | |
| SCHEMBL28702972 | 0.77 | TSHR (0.47) | TSHRALDH1A1NPC1CYP3A4ALOX15 | |
| SCHEMBL5875374 | 0.77 | TSHR (0.47) | TSHRALDH1A1NPC1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482802-A1 | NOVEL PESTICIDE FORMULATIONS | Burnet, Michael (DE) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011040956-A1 | NOVEL PESTICIDE FORMULATIONS | BURNET MICHAEL (DE) | 2011-04-07 | — | — | WO | disclosed |