SCHEMBL1665867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11895090	0.90	NPSR1 (0.37)	CYP1A2METAP2GPBAR1AAK1PDE2A
	SCHEMBL1665866	0.85	BUB1 (0.34)	CYP1A2METAP2GPBAR1AAK1HPGD
	SCHEMBL11894648	0.84	CYP1A2 (0.41)	CYP1A2METAP2GPBAR1AAK1
	SCHEMBL1665870	0.83	ILK (0.53)	CYP1A2METAP2GPBAR1DYRK1A
	SCHEMBL11895093	0.83	RAB9A (0.39)	CYP1A2PDE2APDE10ADYRK1AHPGD
	SCHEMBL11953200	0.83	DYRK1A (0.38)	AAK1PDE10ADYRK1A
	SCHEMBL11894951	0.82	ILK (0.34)	CYP1A2METAP2GPBAR1PDE2APDE10A
	SCHEMBL11895332	0.80	POLB (0.33)	CYP1A2METAP2GPBAR1PDE2APDE10A
	SCHEMBL11895033	0.79	DDR1 (0.41)	DYRK1AHPGD
	SCHEMBL11894806	0.78	ILK (0.32)	GPBAR1PDE2APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.