Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666611 | 0.89 | KEAP1 (0.48) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5053775 | 0.85 | TLR8 (0.50) | ALDH1A1MEN1KMT2AMAPK1TLR8 | |
| Hydrochloric Acid SCHEMBL1666361 | 0.84 | TLR8 (0.52) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL1668543 | 0.84 | TLR8 (0.51) | MEN1KMT2AMAPK1LMNATLR8 | |
| SCHEMBL1666165 | 0.84 | TLR8 (0.53) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL1666047 | 0.84 | TLR8 (0.54) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL1666616 | 0.83 | TLR8 (0.47) | ALDH1A1MEN1KMT2AMAPK1TLR8 | |
| SCHEMBL1666362 | 0.81 | HTT (0.44) | MAPTMEN1KMT2AHTTTLR8 | |
| SCHEMBL1666215 | 0.81 | TLR8 (0.46) | ALDH1A1MEN1KMT2AMAPK1TLR8 | |
| Hydrochloric Acid SCHEMBL1666211 | 0.80 | TLR8 (0.50) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921406-B2 | 5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-12-30 | — | — | US | claimed |
| US-20150183770-A1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2015-07-02 | — | — | US | disclosed |
| US-8921406-B2 | 5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-12-30 | — | — | US | disclosed |
| EP-1917251-B1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2013-04-03 | — | — | EP | disclosed |
| US-20110207788-A1 | 5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2011-08-25 | — | — | US | disclosed |
| EP-2308852-A1 | 5-ring heteroaromatic compounds and their use as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-04-13 | — | — | EP | disclosed |
| EP-1917251-A2 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022947-A2 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183770-A1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | HTR5A, HTR3A, HTR6 | SLC29A1 792/4885MAPT 1760/4885ALDH1A1 1430/4885 |
| US-20110207788-A1 | 5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors | HTR5A, HTR3A, HTR6 | SLC29A1 792/4885MAPT 1760/4885ALDH1A1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.