Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19768885 | 0.79 | RAB9A (0.44) | RAB9ASMN1; SMN2LMNALRRK2ALDH1A1 | |
| SCHEMBL13731080 | 0.79 | NAMPT (0.41) | RAB9ASMN1; SMN2LRRK2ALDH1A1NAMPT | |
| SCHEMBL9901418 | 0.78 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL15472431 | 0.78 | NAMPT (0.44) | RAB9ASMN1; SMN2LRRK2NAMPTNPC1 | |
| SCHEMBL1841864 | 0.76 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL15472433 | 0.75 | NAMPT (0.44) | RAB9ASMN1; SMN2LRRK2NAMPTNPC1 | |
| SCHEMBL1304161 | 0.73 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL30880982 | 0.73 | NAMPT (0.43) | RAB9ASMN1; SMN2LRRK2NAMPTNPC1 | |
| SCHEMBL15474199 | 0.73 | NAMPT (0.41) | RAB9ASMN1; SMN2LRRK2ALDH1A1GAA | |
| SCHEMBL20604093 | 0.73 | WNT3A (0.59) | RAB9ASMN1; SMN2LMNANPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375008-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9247745-B2 | Substituted pyridazines for controlling invertebrate pests | BASF SE (DE) | 2016-02-02 | — | — | US | disclosed |
| EP-2342196-B1 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2015-07-29 | — | — | EP | disclosed |
| EP-2595981-B1 | NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2014-12-10 | — | — | EP | disclosed |
| US-20140142111-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2014-05-22 | — | — | US | disclosed |
| US-8729083-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2014-05-20 | — | — | US | disclosed |
| EP-2595981-A1 | NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130116264-A1 | Novel Hetaryl (thio)carboxamide Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012010534-A1 | NOVEL HETARYL (THIO)CARBOXAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20110269770-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |
| EP-2342196-A1 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010034737-A1 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116264-A1 | Novel Hetaryl (thio)carboxamide Compounds for Controlling Invertebrate Pests | TH, CYP8B1, ETFA | RAB9A 1885/4885SMN1; SMN2 4341/4885LMNA 3119/4885 |
| US-20110269770-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | GRIN2C, GRIN2D, NR2C2 | RAB9A 1969/4885SMN1; SMN2 3228/4885LMNA 1973/4885 |
| US-20140142111-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | NOX3, F3, F2 | RAB9A 2590/4885SMN1; SMN2 3213/4885LMNA 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.