SCHEMBL16660731

SCHEMBL16660731

CCN(C(=O)c1cnn(C2CCCCC2)c1C)c1ccnnc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXTR P30559 2/20 0.40
PKM P14618 1/20 0.37
TRPV4 Q9HBA0 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
CYP2C19 P33261 1/20 0.34
KCNJ6 P48051 2/20 0.34
KCNJ5 P48544 2/20 0.34
KCNJ3 P48549 2/20 0.34
HSD11B1 P28845 2/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CNR2 P34972 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PDE9A O76083 1/20 0.32
PDE1B Q01064 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660742 0.97 OXTR (0.40) OXTRPKMTRPV4CYP3A4CYP2C9
SCHEMBL16660729 0.91 OXTR (0.39) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16973269 0.88 TRPV4 (0.38) OXTRTRPV4CYP3A4CYP2C9CYP2B6
SCHEMBL16660740 0.87 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660732 0.87 OXTR (0.38) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660728 0.86 KMT2A (0.38) PKMTRPV4KCNJ6KCNJ5KCNJ3
SCHEMBL16654825 0.85 OXTR (0.35) OXTRTRPV4CYP3A4CYP2C9CYP2B6
SCHEMBL16660723 0.84 KMT2A (0.38) PKMTRPV4KCNJ6KCNJ5KCNJ3
SCHEMBL16660743 0.84 OXTR (0.39) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16654466 0.84 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015055497-A1 SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2015-04-23 WO disclosed