SCHEMBL16660732

SCHEMBL16660732

CCN(C(=O)c1cnn(C2CCCCC2Cl)c1C)c1ccnnc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXTR P30559 2/20 0.38
TP53 P04637 1/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP2B6 P20813 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
NPSR1 Q6W5P4 2/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
GAA P10253 1/20 0.30
CYP2D6 P10635 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660731 0.87 OXTR (0.40) OXTRCYP3A4CYP2C9CYP2C19CYP2B6
SCHEMBL16660743 0.86 OXTR (0.39) OXTRTP53CYP3A4CYP2C9CYP2C19
SCHEMBL16660742 0.85 OXTR (0.40) OXTRTP53CYP3A4CYP2C9CYP2C19
SCHEMBL16660729 0.82 OXTR (0.39) OXTRTP53CYP3A4CYP2C9CYP2C19
SCHEMBL16973269 0.79 TRPV4 (0.38) OXTRCYP3A4CYP2C9CYP2C19CYP2B6
SCHEMBL16660740 0.78 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2C19CYP2B6
SCHEMBL16654825 0.76 OXTR (0.35) OXTRCYP3A4CYP2C9CYP2C19CYP2B6
SCHEMBL16660721 0.76 NAMPT (0.39) ALDH1A1GAAHTTSMN1; SMN2
SCHEMBL16660741 0.76 OXTR (0.40) OXTRCYP3A4CYP2C9CYP2C19CYP2B6
SCHEMBL16654466 0.76 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2C19CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015055497-A1 SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2015-04-23 WO disclosed